I recently came across a very interesting paper by the research team of Gerald Reaven, an endocrinologist at Stanford. He has long been one of the leading researchers studying insulin resistance, the metabolic syndrome, and their association with obesity. Reaven's research, and that of many others, suggests that insulin resistance is a central part of the constellation of metabolic disturbances that are so common in affluent nations*. We also have good reason to believe that it contributes to cardiovascular risk.
All the way back in 1998, Reaven's group published a paper that should raise the eyebrows of anyone interested in cardiovascular health (1).
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